Effects of phthalic acid esters on fetal health
نویسندگان
چکیده
منابع مشابه
Effects of phthalic acid esters on fetal health.
INTRODUCTION Phthalates are synthetic industrial compounds capable of disrupting endocrine system. Effects of phthalates depend on dosage, duration of action and stage of development of the individual, thus making the fetus, newborn, and children at puberty the most vulnerable groups. METABOLISM OF PHTHALATES: Metabolism of these compounds consists of at least two steps: hydrolysis and conjugat...
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The effects, over periods from 3 days to 9 months of administration, of diets containing di-2-ethylhexyl phthalate are very similar to those observed in rats administered diets containing hypolipidemic drugs such as clofibrate. Changes occur in a characteristic order commencing with alterations in the distribution of lipid within the liver, quickly followed by proliferation of hepatic peroxisom...
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In recent years those in the scientific community concerned with environmental and public health have been called upon to consider two categories of previously unsuspected materials characterized by wide distribution and long persistence in the environment: mercury, especially organic mercury, and the chlorinated diphenyls (PCBs). To a significant extent this conference presents again the same ...
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Each second, the rivers of the world add 109 kg of fresh water to the oceans, and with this water comes tremendous quantities of salts, clay minerals, and other suspended solids. Although the Amazon River makes the largest contribution of fresh water to the sea, its waters are relatively uncontaminated. On the other hand, the Mississippi River, the third largest river, which delivers only about...
متن کاملStudies on the genetic effects of phthalic acid esters on cells in culture.
Mono(2-ethylhexyl) phthalate (MEHP) induced chromosome aberrations in cells of two culture lines, one derived from Chinese hamster ovary cells (CHO) and the other from rat liver cells (RL4). In CHO cells, the clastogenicity of MEHP was unaffected by the presence of an exogenous metabolic activation system (S-9 mix). 2-Ethylhexanol, o-phthalic acid, and phthalic anhydride were without effect. Cy...
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ژورنال
عنوان ژورنال: Medicinski pregled
سال: 2014
ISSN: 0025-8105,1820-7383
DOI: 10.2298/mpns1406172b